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Nucleo–cytoplasmic transport defects and protein aggregates in neurodegeneration

In the ongoing process of uncovering molecular abnormalities in neurodegenerative diseases characterized by toxic protein aggregates, nucleo-cytoplasmic transport defects have an emerging role. Several pieces of evidence suggest a link between neuronal protein inclusions and nuclear pore complex (NP...

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Detalles Bibliográficos
Autores principales: Bitetto, Giacomo, Di Fonzo, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333321/
https://www.ncbi.nlm.nih.gov/pubmed/32616075
http://dx.doi.org/10.1186/s40035-020-00205-2