Impaired autophagy triggered by HDAC9 in mesenchymal stem cells accelerates bone mass loss

BACKGROUND: Bone mass loss in aging is linked with imbalanced lineage differentiation of bone marrow mesenchymal stem cells (BMMSCs). Recent studies have proved that histone deacetylases (HDACs) are regarded as key regulators of bone remodeling. However, HDACs involve in regulating BMMSC bio-behavio...

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Detalles Bibliográficos
Autores principales: Zhang, Liqiang, Qi, Meng, Chen, Ji, Zhao, Jiangdong, Li, Liya, Hu, Jiachen, Jin, Yan, Liu, Wenjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333327/
https://www.ncbi.nlm.nih.gov/pubmed/32620134
http://dx.doi.org/10.1186/s13287-020-01785-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333327/
https://www.ncbi.nlm.nih.gov/pubmed/32620134
http://dx.doi.org/10.1186/s13287-020-01785-6

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