Cargando…

Impaired autophagy triggered by HDAC9 in mesenchymal stem cells accelerates bone mass loss

BACKGROUND: Bone mass loss in aging is linked with imbalanced lineage differentiation of bone marrow mesenchymal stem cells (BMMSCs). Recent studies have proved that histone deacetylases (HDACs) are regarded as key regulators of bone remodeling. However, HDACs involve in regulating BMMSC bio-behavio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Liqiang, Qi, Meng, Chen, Ji, Zhao, Jiangdong, Li, Liya, Hu, Jiachen, Jin, Yan, Liu, Wenjia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333327/ https://www.ncbi.nlm.nih.gov/pubmed/32620134 http://dx.doi.org/10.1186/s13287-020-01785-6

Ejemplares similares

Correction: Impaired autophagy triggered by HDAC9 in mesenchymal stem cells accelerates bone mass loss
por: Zhang, Liqiang, et al.
Publicado: (2022)

Increase in HDAC9 suppresses myoblast differentiation via epigenetic regulation of autophagy in hypoxia
por: Zhang, Zhang, et al.
Publicado: (2019)

Autophagy Maintains the Function of Bone Marrow Mesenchymal Stem Cells to Prevent Estrogen Deficiency-Induced Osteoporosis
por: Qi, Meng, et al.
Publicado: (2017)

Autophagy Maintains the Function of Bone Marrow Mesenchymal Stem Cells to Prevent Estrogen Deficiency-Induced Osteoporosis: Erratum
por: Qi, Meng, et al.
Publicado: (2023)

Mutual inhibition between HDAC9 and miR-17 regulates osteogenesis of human periodontal ligament stem cells in inflammatory conditions
por: Li, Liya, et al.
Publicado: (2018)

Autophagy controls mesenchymal stem cell properties and senescence during bone aging
por: Ma, Yang, et al.
Publicado: (2017)

GSK3β rephosphorylation rescues ALPL deficiency-induced impairment of odontoblastic differentiation of DPSCs
por: Zhang, Liqiang, et al.
Publicado: (2021)

Blocking the association of HDAC4 with MAP1S accelerates autophagy clearance of mutant Huntingtin
por: Yue, Fei, et al.
Publicado: (2015)

HDAC4 blocks autophagy to trigger podocyte injury: non-epigenetic action in diabetic nephropathy
por: Wei, Qingqing, et al.
Publicado: (2014)

Specific Control of Pancreatic Endocrine β- and δ-Cell Mass by Class IIa Histone Deacetylases HDAC4, HDAC5, and HDAC9
por: Lenoir, Olivia, et al.
Publicado: (2011)

Sinusoidal electromagnetic fields accelerate bone regeneration by boosting the multifunctionality of bone marrow mesenchymal stem cells
por: Li, Weigang, et al.
Publicado: (2021)

MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma
por: Fabian, Johannes, et al.
Publicado: (2016)

Loss of chaperone-mediated autophagy is associated with low vertebral cancellous bone mass
por: Akel, Nisreen, et al.
Publicado: (2022)

Knockdown of HDAC9 Inhibits Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells Partially by Suppressing the MAPK Signaling Pathway
por: Wang, Bo, et al.
Publicado: (2022)

Alkaline Phosphatase Controls Lineage Switching of Mesenchymal Stem Cells by Regulating the LRP6/GSK3β Complex in Hypophosphatasia
por: Liu, Wenjia, et al.
Publicado: (2018)

Knockdown of the HDAC1 Promotes the Directed Differentiation of Bone Mesenchymal Stem Cells into Cardiomyocytes
por: Lu, Dong-feng, et al.
Publicado: (2014)

HDAC9 Contributes to Serous Ovarian Cancer Progression through Regulating Epithelial–Mesenchymal Transition
por: Xu, Long, et al.
Publicado: (2022)

HDAC1 and HDAC2 Double Knockout Triggers Cell Apoptosis in Advanced Thyroid Cancer
por: Lin, Ching-Ling, et al.
Publicado: (2019)

The Role of HDAC6 in Autophagy and NLRP3 Inflammasome
por: Chang, Panpan, et al.
Publicado: (2021)

Licochalcone A up-regulates of FasL in mesenchymal stem cells to strengthen bone formation and increase bone mass
por: Ming, Leiguo, et al.
Publicado: (2014)

Mitochondrial dysfunction impairs osteogenesis, increases osteoclast activity, and accelerates age related bone loss
por: Dobson, Philip F., et al.
Publicado: (2020)

Osteocyte β1 integrin loss causes low bone mass and impairs bone mechanotransduction in mice
por: Qin, Lei, et al.
Publicado: (2022)

Loss of decay-accelerating factor triggers podocyte injury and glomerulosclerosis
por: Angeletti, Andrea, et al.
Publicado: (2020)

Hdac1 and Hdac2 regulate the quiescent state and survival of hair-follicle mesenchymal niche
por: Sibony-Benyamini, Hadas, et al.
Publicado: (2023)

Alpl prevents bone ageing sensitivity by specifically regulating senescence and differentiation in mesenchymal stem cells
por: Liu, Wenjia, et al.
Publicado: (2018)

Upregulation of Parkin Accelerates Osteoblastic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells and Bone Regeneration by Enhancing Autophagy and β-Catenin Signaling
por: Zhang, Wei, et al.
Publicado: (2020)

Fluvastatin Prevents Lung Adenocarcinoma Bone Metastasis by Triggering Autophagy
por: Yang, Zuozhang, et al.
Publicado: (2017)

Correction: Alpl prevents bone ageing sensitivity by specifically regulating senescence and differentiation in mesenchymal stem cells
por: Liu, Wenjia, et al.
Publicado: (2020)

MicroRNA-9 promotes the neuronal differentiation of rat bone marrow mesenchymal stem cells by activating autophagy
por: Zhang, Guang-yu, et al.
Publicado: (2015)

HDAC6 Inhibition Extinguishes Autophagy in Cancer: Recent Insights
por: Passaro, Eugenia, et al.
Publicado: (2021)

Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity
por: Hesse, Eric, et al.
Publicado: (2010)

Developmentally engineered bio-assemblies releasing neurotrophic exosomes guide in situ neuroplasticity following spinal cord injury
por: Yan, Jin, et al.
Publicado: (2022)

Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging
por: Khass, Mohamed, et al.
Publicado: (2022)

Loss of hepatic chaperone-mediated autophagy accelerates proteostasis failure in aging
por: Schneider, Jaime L, et al.
Publicado: (2015)

Which is the best (9)Be carrier for (10)Be/(9)Be accelerator mass spectrometry?
por: Merchel, Silke, et al.
Publicado: (2021)

Loss of chemerin triggers bone remodeling in vivo and in vitro
por: Han, Long, et al.
Publicado: (2021)

9th International Conference on Accelerator Mass Spectrometry
por: Nakamura, Toshio, et al.
Publicado: (2004)

Induction of autophagy does not alter the anti-tumor effects of HDAC inhibitors
por: Newbold, A, et al.
Publicado: (2012)

Molecular Determinants of Cancer Therapy Resistance to HDAC Inhibitor-Induced Autophagy
por: Mrakovcic, Maria, et al.
Publicado: (2019)

Mmp13 deletion in mesenchymal cells increases bone mass and may attenuate the cortical bone loss caused by estrogen deficiency
por: Ponte, Filipa, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qiag9kc8b4n7dsfig6g9ohrqbv