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CagA orchestrates eEF1A1 and PKCδ to induce interleukin-6 expression in Helicobacter pylori-infected gastric epithelial cells

BACKGROUND: Helicobacter pylori colonises the stomach of approximately 50% of the global population. Cytotoxin-associated gene A protein (CagA) is one of the important virulent factors responsible for the increased inflammation and increases the risk of developing peptic ulcers and gastric carcinoma...

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Detalles Bibliográficos
Autores principales: Xu, Shaohan, Wu, Xiaoqian, Zhang, Xiaoyan, Chen, Chu, Chen, Hao, She, Feifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333391/
https://www.ncbi.nlm.nih.gov/pubmed/32636937
http://dx.doi.org/10.1186/s13099-020-00368-3