meQTL and ncRNA functional analyses of 102 GWAS-SNPs associated with depression implicate HACE1 and SHANK2 genes

BACKGROUND: Little is known about how genetics and epigenetics interplay in depression. Evidence suggests that genetic variants may change vulnerability to depression by modulating DNA methylation (DNAm) and non-coding RNA (ncRNA) levels. Therefore, the aim of the study was to investigate the effect...

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Detalles Bibliográficos
Autores principales: Ciuculete, Diana M., Voisin, Sarah, Kular, Lara, Jonsson, Jörgen, Rask-Andersen, Mathias, Mwinyi, Jessica, Schiöth, Helgi B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333393/
https://www.ncbi.nlm.nih.gov/pubmed/32616021
http://dx.doi.org/10.1186/s13148-020-00884-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333393/
https://www.ncbi.nlm.nih.gov/pubmed/32616021
http://dx.doi.org/10.1186/s13148-020-00884-8

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