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meQTL and ncRNA functional analyses of 102 GWAS-SNPs associated with depression implicate HACE1 and SHANK2 genes
BACKGROUND: Little is known about how genetics and epigenetics interplay in depression. Evidence suggests that genetic variants may change vulnerability to depression by modulating DNA methylation (DNAm) and non-coding RNA (ncRNA) levels. Therefore, the aim of the study was to investigate the effect...
Autores principales: | Ciuculete, Diana M., Voisin, Sarah, Kular, Lara, Jonsson, Jörgen, Rask-Andersen, Mathias, Mwinyi, Jessica, Schiöth, Helgi B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333393/ https://www.ncbi.nlm.nih.gov/pubmed/32616021 http://dx.doi.org/10.1186/s13148-020-00884-8 |
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