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The immune-checkpoint HLA-G/ILT4 is involved in the regulation of VEGF expression in clear cell renal cell carcinoma

BACKGROUND: Clear cell renal cell carcinoma (ccRCC), the most aggressive renal cancer, is characterized by early lymph node metastases and bad prognosis. Most therapies targeting advanced or metastatic ccRCC are based, as first-line treatment, on the administration of the vascular endothelial growth...

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Detalles Bibliográficos
Autores principales: García, Marcela, Palma, Maria Belen, Verine, Jerome, Miriuka, Santiago, Inda, Ana M., Errecalde, Ana L., Desgrandchamps, François, Carosella, Edgardo D., Tronik-Le Roux, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333411/
https://www.ncbi.nlm.nih.gov/pubmed/32620162
http://dx.doi.org/10.1186/s12885-020-07113-8