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A Gq Biased Small Molecule Active at the TSH Receptor

G protein coupled receptors (GPCRs) can lead to G protein and non-G protein initiated signals. By virtue of its structural property, the TSH receptor (TSHR) has a unique ability to engage different G proteins making it highly amenable to selective signaling. In this study, we describe the identifica...

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Detalles Bibliográficos
Autores principales: Latif, Rauf, Morshed, Syed A., Ma, Risheng, Tokat, Bengu, Mezei, Mihaly, Davies, Terry F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333667/
https://www.ncbi.nlm.nih.gov/pubmed/32676053
http://dx.doi.org/10.3389/fendo.2020.00372