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A Gq Biased Small Molecule Active at the TSH Receptor
G protein coupled receptors (GPCRs) can lead to G protein and non-G protein initiated signals. By virtue of its structural property, the TSH receptor (TSHR) has a unique ability to engage different G proteins making it highly amenable to selective signaling. In this study, we describe the identifica...
Autores principales: | Latif, Rauf, Morshed, Syed A., Ma, Risheng, Tokat, Bengu, Mezei, Mihaly, Davies, Terry F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333667/ https://www.ncbi.nlm.nih.gov/pubmed/32676053 http://dx.doi.org/10.3389/fendo.2020.00372 |
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