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Neoantigen-Specific Adoptive Cell Therapies for Cancer: Making T-Cell Products More Personal

Mutation-derived neoantigens are taking central stage as a determinant in eliciting effective antitumor immune responses following adoptive T-cell therapies. These mutations are patient-specific, and their targeting calls for highly personalized pipelines. The promising clinical outcomes of tumor-in...

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Detalles Bibliográficos
Autores principales: Bianchi, Valentina, Harari, Alexandre, Coukos, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333784/
https://www.ncbi.nlm.nih.gov/pubmed/32695101
http://dx.doi.org/10.3389/fimmu.2020.01215