Cargando…
Neoantigen-Specific Adoptive Cell Therapies for Cancer: Making T-Cell Products More Personal
Mutation-derived neoantigens are taking central stage as a determinant in eliciting effective antitumor immune responses following adoptive T-cell therapies. These mutations are patient-specific, and their targeting calls for highly personalized pipelines. The promising clinical outcomes of tumor-in...
Autores principales: | Bianchi, Valentina, Harari, Alexandre, Coukos, George |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333784/ https://www.ncbi.nlm.nih.gov/pubmed/32695101 http://dx.doi.org/10.3389/fimmu.2020.01215 |
Ejemplares similares
-
Adoptive Cell Therapy Targeting Neoantigens: A Frontier for Cancer Research
por: Wang, Zhidong, et al.
Publicado: (2020) -
Selection of Shared and Neoantigen-Reactive T Cells for Adoptive Cell Therapy Based on CD137 Separation
por: Seliktar-Ofir, Sivan, et al.
Publicado: (2017) -
‘Hotspots’ of Antigen Presentation Revealed by Human Leukocyte Antigen Ligandomics for Neoantigen Prioritization
por: Müller, Markus, et al.
Publicado: (2017) -
Advances in identification and selection of personalized neoantigen/T-cell pairs for autologous adoptive T cell therapies
por: Kast, Florian, et al.
Publicado: (2021) -
Towards next‐generation TIL therapy: TILs enriched in neoepitope‐specific T cells
por: Arnaud, Marion, et al.
Publicado: (2023)