Reverse swing‐M, phase 1 study of repurposing mebendazole in recurrent high‐grade glioma

BACKGROUND: Relapsed high‐grade glioma has dismal outcomes. Mebendazole has shown promising activity against glioma in in‐vitro and in‐vivo studies. Hence, we undertook a phase 1 study to repurpose mebendazole in the treatment of glioblastoma. METHODS: We conducted a phase 1 study (accelerated titra...

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Detalles Bibliográficos
Autores principales: Patil, Vijay M., Bhelekar, Arti, Menon, Nandini, Bhattacharjee, Atanu, Simha, Vijai, Abhinav, Ram, Abhyankar, Anuja, Sridhar, Epari, Mahajan, Abhishek, Puranik, Ameya D., Purandare, Nilendu, Janu, Amit, Ahuja, Ankita, Krishnatry, Rahul, Gupta, Tejpal, Jalali, Rakesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Clinical Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333848/
https://www.ncbi.nlm.nih.gov/pubmed/32400117
http://dx.doi.org/10.1002/cam4.3094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333848/
https://www.ncbi.nlm.nih.gov/pubmed/32400117
http://dx.doi.org/10.1002/cam4.3094

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