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Reverse swing‐M, phase 1 study of repurposing mebendazole in recurrent high‐grade glioma
BACKGROUND: Relapsed high‐grade glioma has dismal outcomes. Mebendazole has shown promising activity against glioma in in‐vitro and in‐vivo studies. Hence, we undertook a phase 1 study to repurpose mebendazole in the treatment of glioblastoma. METHODS: We conducted a phase 1 study (accelerated titra...
Autores principales: | Patil, Vijay M., Bhelekar, Arti, Menon, Nandini, Bhattacharjee, Atanu, Simha, Vijai, Abhinav, Ram, Abhyankar, Anuja, Sridhar, Epari, Mahajan, Abhishek, Puranik, Ameya D., Purandare, Nilendu, Janu, Amit, Ahuja, Ankita, Krishnatry, Rahul, Gupta, Tejpal, Jalali, Rakesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333848/ https://www.ncbi.nlm.nih.gov/pubmed/32400117 http://dx.doi.org/10.1002/cam4.3094 |
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