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KEAP1, a cysteine-based sensor and a drug target for the prevention and treatment of chronic disease
Redox imbalance and persistent inflammation are the underlying causes of most chronic diseases. Mammalian cells have evolved elaborate mechanisms for restoring redox homeostasis and resolving acute inflammatory responses. One prominent mechanism is that of inducing the expression of antioxidant, ant...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333886/ https://www.ncbi.nlm.nih.gov/pubmed/32574549 http://dx.doi.org/10.1098/rsob.200105 |