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Anti-EGFR therapy in metastatic colorectal cancer: mechanisms and potential regimens of drug resistance
Cetuximab and panitumumab, as the highly effective antibodies targeting epidermal growth factor receptor (EGFR), have clinical activity in the patients with metastatic colorectal cancer (mCRC). These agents have good curative efficacy, but drug resistance also exists at the same time. The effects of...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333932/ https://www.ncbi.nlm.nih.gov/pubmed/32665850 http://dx.doi.org/10.1093/gastro/goaa026 |