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Anti-EGFR therapy in metastatic colorectal cancer: mechanisms and potential regimens of drug resistance

Cetuximab and panitumumab, as the highly effective antibodies targeting epidermal growth factor receptor (EGFR), have clinical activity in the patients with metastatic colorectal cancer (mCRC). These agents have good curative efficacy, but drug resistance also exists at the same time. The effects of...

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Detalles Bibliográficos
Autores principales: Li, Qing-Hai, Wang, Ying-Zhao, Tu, Jian, Liu, Chu-Wei, Yuan, Yu-Jie, Lin, Run, He, Wei-Ling, Cai, Shi-Rong, He, Yu-Long, Ye, Jin-Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333932/
https://www.ncbi.nlm.nih.gov/pubmed/32665850
http://dx.doi.org/10.1093/gastro/goaa026