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Decoding whole-genome mutational signatures in 37 human pan-cancers by denoising sparse autoencoder neural network

Millions of somatic mutations have recently been discovered in cancer genomes. These mutations in cancer genomes occur due to internal and external mutagenesis forces. Decoding the mutational processes by examining their unique patterns has successfully revealed many known and novel signatures from...

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Detalles Bibliográficos
Autores principales: Pei, Guangsheng, Hu, Ruifeng, Dai, Yulin, Zhao, Zhongming, Jia, Peilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334101/
https://www.ncbi.nlm.nih.gov/pubmed/32528130
http://dx.doi.org/10.1038/s41388-020-1343-z