A sequential methodology for the rapid identification and characterization of breast cancer-associated functional SNPs

GWAS cannot identify functional SNPs (fSNP) from disease-associated SNPs in linkage disequilibrium (LD). Here, we report developing three sequential methodologies including Reel-seq (Regulatory element-sequencing) to identify fSNPs in a high-throughput fashion, SDCP-MS (SNP-specific DNA competition...

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Detalles Bibliográficos
Autores principales: Zhao, Yihan, Wu, Di, Jiang, Danli, Zhang, Xiaoyu, Wu, Ting, Cui, Jing, Qian, Min, Zhao, Jean, Oesterreich, Steffi, Sun, Wei, Finkel, Toren, Li, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334201/
https://www.ncbi.nlm.nih.gov/pubmed/32620845
http://dx.doi.org/10.1038/s41467-020-17159-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334201/
https://www.ncbi.nlm.nih.gov/pubmed/32620845
http://dx.doi.org/10.1038/s41467-020-17159-8

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