Cargando…

Geometric regulation of histone state directs melanoma reprogramming

Malignant melanoma displays a high degree of cellular plasticity during disease progression. Signals in the tumor microenvironment are believed to influence melanoma plasticity through changes in the epigenetic state to guide dynamic differentiation and de-differentiation. Here we uncover a relation...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Junmin, Molley, Thomas G., Seward, Christopher H., Abdeen, Amr A., Zhang, Huimin, Wang, Xiaochun, Gandhi, Hetvi, Yang, Jia-Lin, Gaus, Katharina, Kilian, Kristopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334222/
https://www.ncbi.nlm.nih.gov/pubmed/32620903
http://dx.doi.org/10.1038/s42003-020-1067-1