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Cytosolic phospholipase A(2)-α participates in lipid body formation and PGE(2) release in human neutrophils stimulated with an l-amino acid oxidase from Calloselasma rhodostoma venom

Cr-LAAO, an l-amino acid oxidase isolated from Calloselasma rhodosthoma snake venom, has been demonstrated as a potent stimulus for neutrophil activation and inflammatory mediator production. However, the mechanisms involved in Cr-LAAO induced neutrophil activation has not been well characterized. H...

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Detalles Bibliográficos
Autores principales: Paloschi, Mauro Valentino, Lopes, Jéssica Amaral, Boeno, Charles Nunes, Silva, Milena Daniela Souza, Evangelista, Jaína Rodrigues, Pontes, Adriana Silva, da Silva Setúbal, Sulamita, Rego, Cristina Matiele Alves, Néry, Neriane Monteiro, Ferreira e Ferreira, Alex Augusto, Pires, Weverson Luciano, Felipin, Kátia Paula, Ferreira, Gabriel Eduardo Melim, Bozza, Patrícia Torres, Zuliani, Juliana Pavan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334223/
https://www.ncbi.nlm.nih.gov/pubmed/32620771
http://dx.doi.org/10.1038/s41598-020-67345-3