Development of a capillary electrophoresis–mass spectrometry method for the analysis of metformin and its transformation product guanylurea in biota

A method with capillary electrophoresis coupled to mass spectrometry was optimized to determine the uptake of metformin and its metabolite guanylurea by zebrafish (Danio rerio) embryos and brown trout (Salmo trutta f. fario) exposed under laboratory conditions. Metformin was extracted from fish tiss...

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Detalles Bibliográficos
Autores principales: Knoll, Sarah, Jacob, Stefanie, Mieck, Susanna, Triebskorn, Rita, Braunbeck, Thomas, Huhn, Carolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334255/
https://www.ncbi.nlm.nih.gov/pubmed/32572543
http://dx.doi.org/10.1007/s00216-020-02759-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334255/
https://www.ncbi.nlm.nih.gov/pubmed/32572543
http://dx.doi.org/10.1007/s00216-020-02759-6

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