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Broadly neutralizing antibodies potently inhibit cell-to-cell transmission of semen leukocyte-derived SHIV162P3

BACKGROUND: HIV-1 sexual transmission occurs mostly through infected semen, which contains both free virions and infected leukocytes. Transmission initiated by infected cells has been shown by several in vitro and in vivo studies and a reduced capacity of broadly neutralizing antibodies (bNAbs) to i...

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Detalles Bibliográficos
Autores principales: Suphaphiphat, Karunasinee, Tolazzi, Monica, Hua, Stéphane, Desjardins, Delphine, Lorin, Valerie, Dereuddre-Bosquet, Nathalie, Mouquet, Hugo, Scarlatti, Gabriella, Grand, Roger Le, Cavarelli, Mariangela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334370/
https://www.ncbi.nlm.nih.gov/pubmed/32619962
http://dx.doi.org/10.1016/j.ebiom.2020.102842