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Specific O-GlcNAc modification at Ser-615 modulates eNOS function

Idiopathic pulmonary arterial hypertension (IPAH) is a progressive and devastating disease characterized by vascular smooth muscle and endothelial cell proliferation leading to a narrowing of the vessels in the lung. The increased resistance in the lung and the higher pressures generated result in r...

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Detalles Bibliográficos
Autores principales: Aulak, Kulwant S., Barnes, Jarrod W., Tian, Liping, Mellor, Noel E., Haque, Mohammad M., Willard, Belinda, Li, Ling, Comhair, Suzy C., Stuehr, Dennis J., Dweik, Raed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334407/
https://www.ncbi.nlm.nih.gov/pubmed/32863226
http://dx.doi.org/10.1016/j.redox.2020.101625