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CD44v8-10 mRNA contained in serum exosomes as a diagnostic marker for docetaxel resistance in prostate cancer patients

BACKGROUND: Docetaxel is first-line chemotherapy for castration-resistant prostate cancer (CRPC), but most patients acquire docetaxel resistance. CD44 has been shown to be involved in drug resistance of cancers including prostate cancer. We hypothesized that CD44 in serum exosomes could be a diagnos...

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Detalles Bibliográficos
Autores principales: Kato, Taku, Mizutani, Kosuke, Kawakami, Kyojiro, Fujita, Yasunori, Ehara, Hidetoshi, Ito, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334415/
https://www.ncbi.nlm.nih.gov/pubmed/32642575
http://dx.doi.org/10.1016/j.heliyon.2020.e04138