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Long-term association of a transcription factor with its chromatin binding site can stabilize gene expression and cell fate commitment
Some lineage-determining transcription factors are overwhelmingly important in directing embryonic cells to a particular differentiation pathway, such as Ascl1 for nerve. They also have an exceptionally strong ability to force cells to change from an unrelated pathway to one preferred by their actio...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334453/ https://www.ncbi.nlm.nih.gov/pubmed/32532919 http://dx.doi.org/10.1073/pnas.2000467117 |