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Engineering Escherichia coli to improve tryptophan production via genetic manipulation of precursor and cofactor pathways

Optimizing the supply of biosynthetic precursors and cofactors is usually an effective metabolic strategy to improve the production of target compounds. Here, the combination of optimizing precursor synthesis and balancing cofactor metabolism was adopted to improve tryptophan production in Escherich...

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Detalles Bibliográficos
Autores principales: Li, Zhu, Ding, Dongqin, Wang, Huiying, Liu, Linxia, Fang, Huan, Chen, Tao, Zhang, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334480/
https://www.ncbi.nlm.nih.gov/pubmed/32671235
http://dx.doi.org/10.1016/j.synbio.2020.06.009