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Magnetically Directed Enzyme/Prodrug Prostate Cancer Therapy Based on β-Glucosidase/Amygdalin

BACKGROUND: β-Glucosidase (β-Glu) can activate amygdalin to kill prostate cancer cells, but the poor specificity of this killing effect may cause severe general toxicity in vivo, limiting the practical clinical application of this approach. MATERIALS AND METHODS: In this study, starch-coated magneti...

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Detalles Bibliográficos
Autores principales: Zhou, Jie, Hou, Jing, Rao, Jun, Zhou, Conghui, Liu, Yunlong, Gao, Wenxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334483/
https://www.ncbi.nlm.nih.gov/pubmed/32636623
http://dx.doi.org/10.2147/IJN.S242359