Cargando…
Improving protein solubility and activity by introducing small peptide tags designed with machine learning models
Improving catalytic ability of enzymes is critical to the success of many metabolic engineering projects, but the search space of possible protein mutants is too large to explore exhaustively through experiments. To some extent, highly soluble enzymes tend to exhibit high activity due to their bette...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334598/ https://www.ncbi.nlm.nih.gov/pubmed/32642423 http://dx.doi.org/10.1016/j.mec.2020.e00138 |