Metformin alleviates lead-induced mitochondrial fragmentation via AMPK/Nrf2 activation in SH-SY5Y cells

As a widely acknowledged environmental pollutant, lead (Pb) exhibits neurological toxicity primarily due to the vulnerability of neural system. It is suggested that Pb could perturb mitochondrial function, triggering the following disturbance of cellular homeostasis. Here, we focused on the role of...

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Detalles Bibliográficos
Autores principales: Yang, Luoyao, Li, Xiaoyi, Jiang, Anli, Li, Xintong, Chang, Wei, Chen, Jun, Ye, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334619/
https://www.ncbi.nlm.nih.gov/pubmed/32863218
http://dx.doi.org/10.1016/j.redox.2020.101626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334619/
https://www.ncbi.nlm.nih.gov/pubmed/32863218
http://dx.doi.org/10.1016/j.redox.2020.101626

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