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Modulation of LPS-induced inflammatory cytokine production by a novel glycogen synthase kinase-3 inhibitor

Sepsis is a serious condition that can lead to long-term organ damage and death. At the molecular level, the hallmark of sepsis is the elevated expression of a multitude of potent cytokines, i.e. a cytokine storm. For sepsis involving gram-negative bacteria, macrophages recognize lipopolysaccharide...

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Detalles Bibliográficos
Autores principales: Noori, Mahboubeh S., Courreges, Maria C., Bergmeier, Stephen C., McCall, Kelly D., Goetz, Douglas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334664/
https://www.ncbi.nlm.nih.gov/pubmed/32634441
http://dx.doi.org/10.1016/j.ejphar.2020.173340