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immuneSIM: tunable multi-feature simulation of B- and T-cell receptor repertoires for immunoinformatics benchmarking

SUMMARY: B- and T-cell receptor repertoires of the adaptive immune system have become a key target for diagnostics and therapeutics research. Consequently, there is a rapidly growing number of bioinformatics tools for immune repertoire analysis. Benchmarking of such tools is crucial for ensuring rep...

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Detalles Bibliográficos
Autores principales: Weber, Cédric R, Akbar, Rahmad, Yermanos, Alexander, Pavlović, Milena, Snapkov, Igor, Sandve, Geir K, Reddy, Sai T, Greiff, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334888/
https://www.ncbi.nlm.nih.gov/pubmed/32154832
http://dx.doi.org/10.1093/bioinformatics/btaa158