Lower Ca(2+) enhances the K(+)-induced force depression in normal and HyperKPP mouse muscles

Hyperkalemic periodic paralysis (HyperKPP) manifests as stiffness or subclinical myotonic discharges before or during periods of episodic muscle weakness or paralysis. Ingestion of Ca(2+) alleviates HyperKPP symptoms, but the mechanism is unknown because lowering extracellular [Ca(2+)] ([Ca(2+)](e))...

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Detalles Bibliográficos
Autores principales: Uwera, Francine, Ammar, Tarek, McRae, Callum, Hayward, Lawrence J., Renaud, Jean-Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335014/
https://www.ncbi.nlm.nih.gov/pubmed/32291438
http://dx.doi.org/10.1085/jgp.201912511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335014/
https://www.ncbi.nlm.nih.gov/pubmed/32291438
http://dx.doi.org/10.1085/jgp.201912511

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