Characterization of an alternative BAK-binding site for BH3 peptides

Many cellular stresses are transduced into apoptotic signals through modification or up-regulation of the BH3-only subfamily of BCL2 proteins. Through direct or indirect mechanisms, these proteins activate BAK and BAX to permeabilize the mitochondrial outer membrane. While the BH3-only proteins BIM,...

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Detalles Bibliográficos
Autores principales: Ye, Kaiqin, Meng, Wei X., Sun, Hongbin, Wu, Bo, Chen, Meng, Pang, Yuan-Ping, Gao, Jia, Wang, Hongzhi, Wang, Junfeng, Kaufmann, Scott H., Dai, Haiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335050/
https://www.ncbi.nlm.nih.gov/pubmed/32620849
http://dx.doi.org/10.1038/s41467-020-17074-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335050/
https://www.ncbi.nlm.nih.gov/pubmed/32620849
http://dx.doi.org/10.1038/s41467-020-17074-y

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