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Salmonella-based platform for efficient delivery of functional binding proteins to the cytosol

Protein-based affinity reagents (like antibodies or alternative binding scaffolds) offer wide-ranging applications for basic research and therapeutic approaches. However, whereas small chemical molecules efficiently reach intracellular targets, the delivery of macromolecules into the cytosol of cell...

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Detalles Bibliográficos
Autores principales: Chabloz, Antoine, Schaefer, Jonas V., Kozieradzki, Ivona, Cronin, Shane J. F., Strebinger, Daniel, Macaluso, Francesca, Wald, Jiri, Rabbitts, Terence H., Plückthun, Andreas, Marlovits, Thomas C., Penninger, Josef M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335062/
https://www.ncbi.nlm.nih.gov/pubmed/32620833
http://dx.doi.org/10.1038/s42003-020-1072-4