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Functional and transcriptional characterization of complex neuronal co-cultures

Brain-on-a-chip systems are designed to simulate brain activity using traditional in vitro cell culture on an engineered platform. It is a noninvasive tool to screen new drugs, evaluate toxicants, and elucidate disease mechanisms. However, successful recapitulation of brain function on these systems...

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Detalles Bibliográficos
Autores principales: Enright, Heather A., Lam, Doris, Sebastian, Aimy, Sales, Ana Paula, Cadena, Jose, Hum, Nicholas R., Osburn, Joanne J., Peters, Sandra K. G., Petkus, Bryan, Soscia, David A., Kulp, Kristen S., Loots, Gabriela G., Wheeler, Elizabeth K., Fischer, Nicholas O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335084/
https://www.ncbi.nlm.nih.gov/pubmed/32620908
http://dx.doi.org/10.1038/s41598-020-67691-2