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Functional and transcriptional characterization of complex neuronal co-cultures
Brain-on-a-chip systems are designed to simulate brain activity using traditional in vitro cell culture on an engineered platform. It is a noninvasive tool to screen new drugs, evaluate toxicants, and elucidate disease mechanisms. However, successful recapitulation of brain function on these systems...
Autores principales: | Enright, Heather A., Lam, Doris, Sebastian, Aimy, Sales, Ana Paula, Cadena, Jose, Hum, Nicholas R., Osburn, Joanne J., Peters, Sandra K. G., Petkus, Bryan, Soscia, David A., Kulp, Kristen S., Loots, Gabriela G., Wheeler, Elizabeth K., Fischer, Nicholas O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335084/ https://www.ncbi.nlm.nih.gov/pubmed/32620908 http://dx.doi.org/10.1038/s41598-020-67691-2 |
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