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Super-assembly of ER-phagy receptor Atg40 induces local ER remodeling at contacts with forming autophagosomal membranes

The endoplasmic reticulum (ER) is selectively degraded by autophagy (ER-phagy) through proteins called ER-phagy receptors. In Saccharomyces cerevisiae, Atg40 acts as an ER-phagy receptor to sequester ER fragments into autophagosomes by binding Atg8 on forming autophagosomal membranes. During ER-phag...

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Detalles Bibliográficos
Autores principales: Mochida, Keisuke, Yamasaki, Akinori, Matoba, Kazuaki, Kirisako, Hiromi, Noda, Nobuo N., Nakatogawa, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335187/
https://www.ncbi.nlm.nih.gov/pubmed/32620754
http://dx.doi.org/10.1038/s41467-020-17163-y