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Novel thymoquinone lipidic core nanocapsules with anisamide-polymethacrylate shell for colon cancer cells overexpressing sigma receptors

The biggest challenge in colorectal cancer therapy is to avoid intestinal drug absorption before reaching the colon, while focusing on tumor specific delivery with high local concentration and minimal toxicity. In our work, thymoquinone (TQ)-loaded polymeric nanocapsules were prepared using the nano...

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Detalles Bibliográficos
Autores principales: Ramzy, Lydia, Metwally, Abdelkader A., Nasr, Maha, Awad, Gehanne A. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335198/
https://www.ncbi.nlm.nih.gov/pubmed/32620860
http://dx.doi.org/10.1038/s41598-020-67748-2