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LACTB Regulates PIK3R3 to Promote Autophagy and Inhibit EMT and Proliferation Through the PI3K/AKT/mTOR Signaling Pathway in Colorectal Cancer

BACKGROUND: Colorectal cancer (CRC) is one of the most common aggressive malignancies. LACTB functions as a tumor suppressor, and previous findings have demonstrated that LACTB can inhibit epithelial-to-mesenchymal transition (EMT) and proliferation of breast cancer and CRC cells. However, few studi...

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Detalles Bibliográficos
Autores principales: Xu, Wei, Yu, Minhao, Qin, Jun, Luo, Yang, Zhong, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335311/
https://www.ncbi.nlm.nih.gov/pubmed/32636680
http://dx.doi.org/10.2147/CMAR.S250661