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EBV renders B cells susceptible to HIV-1 in humanized mice

HIV and EBV are human pathogens that cause a considerable burden to worldwide health. In combination, these viruses are linked to AIDS-associated lymphomas. We found that EBV, which transforms B cells, renders them susceptible to HIV-1 infection in a CXCR4 and CD4-dependent manner in vitro and that...

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Detalles Bibliográficos
Autores principales: McHugh, Donal, Myburgh, Renier, Caduff, Nicole, Spohn, Michael, Kok, Yik Lim, Keller, Christian W, Murer, Anita, Chatterjee, Bithi, Rühl, Julia, Engelmann, Christine, Chijioke, Obinna, Quast, Isaak, Shilaih, Mohaned, Strouvelle, Victoria P, Neumann, Kathrin, Menter, Thomas, Dirnhofer, Stephan, Lam, Janice KP, Hui, Kwai F, Bredl, Simon, Schlaepfer, Erika, Sorce, Silvia, Zbinden, Andrea, Capaul, Riccarda, Lünemann, Jan D, Aguzzi, Adriano, Chiang, Alan KS, Kempf, Werner, Trkola, Alexandra, Metzner, Karin J, Manz, Markus G, Grundhoff, Adam, Speck, Roberto F, Münz, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335381/
https://www.ncbi.nlm.nih.gov/pubmed/32576602
http://dx.doi.org/10.26508/lsa.202000640