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Prion infection, transmission, and cytopathology modeled in a low-biohazard human cell line
Transmission of prion infectivity to susceptible murine cell lines has simplified prion titration assays and has greatly reduced the need for animal experimentation. However, murine cell models suffer from technical and biological constraints. Human cell lines might be more useful, but they are much...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335386/ https://www.ncbi.nlm.nih.gov/pubmed/32606072 http://dx.doi.org/10.26508/lsa.202000814 |