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Prion infection, transmission, and cytopathology modeled in a low-biohazard human cell line

Transmission of prion infectivity to susceptible murine cell lines has simplified prion titration assays and has greatly reduced the need for animal experimentation. However, murine cell models suffer from technical and biological constraints. Human cell lines might be more useful, but they are much...

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Detalles Bibliográficos
Autores principales:	Avar, Merve, Heinzer, Daniel, Steinke, Nicolas, Doğançay, Berre, Moos, Rita, Lugan, Severine, Cosenza, Claudia, Hornemann, Simone, Andréoletti, Olivier, Aguzzi, Adriano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335386/ https://www.ncbi.nlm.nih.gov/pubmed/32606072 http://dx.doi.org/10.26508/lsa.202000814

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