Stim1 Polymorphism Disrupts Immune Signaling and Creates Renal Injury in Hypertension

BACKGROUND: Spontaneously hypertensive rats of the stroke‐prone line (SHR‐A3) develop hypertensive renal disease as a result of naturally occurring genetic variation. Our prior work identified a single‐nucleotide polymorphism unique to SHR‐A3 that results in truncation of the carboxy terminus of STI...

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Detalles Bibliográficos
Autores principales: Dhande, Isha S., Zhu, Yaming, Kneedler, Sterling C., Joshi, Aniket S., Hicks, M. John, Wenderfer, Scott E., Braun, Michael C., Doris, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335582/
https://www.ncbi.nlm.nih.gov/pubmed/32075490
http://dx.doi.org/10.1161/JAHA.119.014142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335582/
https://www.ncbi.nlm.nih.gov/pubmed/32075490
http://dx.doi.org/10.1161/JAHA.119.014142

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