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Stim1 Polymorphism Disrupts Immune Signaling and Creates Renal Injury in Hypertension
BACKGROUND: Spontaneously hypertensive rats of the stroke‐prone line (SHR‐A3) develop hypertensive renal disease as a result of naturally occurring genetic variation. Our prior work identified a single‐nucleotide polymorphism unique to SHR‐A3 that results in truncation of the carboxy terminus of STI...
Autores principales: | Dhande, Isha S., Zhu, Yaming, Kneedler, Sterling C., Joshi, Aniket S., Hicks, M. John, Wenderfer, Scott E., Braun, Michael C., Doris, Peter A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335582/ https://www.ncbi.nlm.nih.gov/pubmed/32075490 http://dx.doi.org/10.1161/JAHA.119.014142 |
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