Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking

RUNX1 has recently been shown to play an important role in determination of mammary epithelial cell identity. However, mechanisms by which loss of the RUNX1 transcription factor in mammary epithelial cells leads to epithelial-to-mesenchymal transition (EMT) are not known. Here, we report that intera...

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Detalles Bibliográficos
Autores principales: Rose, Joshua T., Moskovitz, Eliana, Boyd, Joseph R., Gordon, Jonathan A., Bouffard, Nicole A., Fritz, Andrew J., Illendula, Anuradha, Bushweller, John H., Lian, Jane B., Stein, Janet L., Zaidi, Sayyed K., Stein, Gary S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335667/
https://www.ncbi.nlm.nih.gov/pubmed/32655837
http://dx.doi.org/10.18632/oncotarget.27637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335667/
https://www.ncbi.nlm.nih.gov/pubmed/32655837
http://dx.doi.org/10.18632/oncotarget.27637

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