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IGF-1 and hyperglycaemia-induced FOXA1 and IGFBP-2 affect epithelial to mesenchymal transition in prostate epithelial cells

Localized prostate cancer (PCa) is a manageable disease but for most men with metastatic disease, it is often fatal. A western diet has been linked with PCa progression and hyperglycaemia has been associated with the risk of lethal and fatal prostate cancer. Using PCa cell lines, we examined the imp...

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Detalles Bibliográficos
Autores principales: Mansor, Rehanna, Holly, Jeff, Barker, Rachel, Biernacka, Kalina, Zielinska, Hanna, Koupparis, Anthony, Rowe, Edward, Oxley, Jon, Sewell, Alex, Martin, Richard M., Lane, Athene, Hackshaw-McGeagh, Lucy, Perks, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335671/
https://www.ncbi.nlm.nih.gov/pubmed/32655839
http://dx.doi.org/10.18632/oncotarget.27650