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miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells
Many cancers maintain an inflammatory microenvironment to promote their growth. Lung cancer is of particular importance, as it is the deadliest cancer worldwide. One inflammatory pathway commonly dysregulated in cancer is the metabolism of arachidonic acid (AA) by Cyclooxygenase-2 (COX-2) and micros...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335672/ https://www.ncbi.nlm.nih.gov/pubmed/32655834 http://dx.doi.org/10.18632/oncotarget.27614 |