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A New Pharmacokinetic Model Describing the Biodistribution of Intravenously and Intratumorally Administered Superparamagnetic Iron Oxide Nanoparticles (SPIONs) in a GL261 Xenograft Glioblastoma Model

BACKGROUND: Superparamagnetic iron oxide nanoparticles (SPIONs) have displayed multifunctional applications in cancer theranostics following systemic delivery. In an effort to increase the therapeutic potential of local therapies (including focal hyperthermia), nanoparticles can also be administered...

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Detalles Bibliográficos
Autores principales: Klapproth, Alexander P, Shevtsov, Maxim, Stangl, Stefan, Li, Wei Bo, Multhoff, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335747/
https://www.ncbi.nlm.nih.gov/pubmed/32669844
http://dx.doi.org/10.2147/IJN.S254745