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A New Pharmacokinetic Model Describing the Biodistribution of Intravenously and Intratumorally Administered Superparamagnetic Iron Oxide Nanoparticles (SPIONs) in a GL261 Xenograft Glioblastoma Model
BACKGROUND: Superparamagnetic iron oxide nanoparticles (SPIONs) have displayed multifunctional applications in cancer theranostics following systemic delivery. In an effort to increase the therapeutic potential of local therapies (including focal hyperthermia), nanoparticles can also be administered...
Autores principales: | Klapproth, Alexander P, Shevtsov, Maxim, Stangl, Stefan, Li, Wei Bo, Multhoff, Gabriele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335747/ https://www.ncbi.nlm.nih.gov/pubmed/32669844 http://dx.doi.org/10.2147/IJN.S254745 |
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