Experimental and theoretical study on structure-tautomerism among edaravone, isoxazolone, and their heterocycles derivatives as antioxidants

Edaravone is a heterocyclic pyrazolone compound. It has pronounced effect against free radicals, however renal and hepatic disorders have been reported. Isoxazolones are considered bioisosteric analogues of pyrazolones and may have comparable properties. Thus, we investigated the structural and elec...

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Detalles Bibliográficos
Autores principales: Queiroz, Auriekson N., Martins, Camila C., Santos, Kelton L.B., Carvalho, Ederson S., Owiti, Alex O., Oliveira, Karen R.M., Herculano, Anderson M., da Silva, Albérico B.F., Borges, Rosivaldo S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335820/
https://www.ncbi.nlm.nih.gov/pubmed/32647483
http://dx.doi.org/10.1016/j.jsps.2020.06.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335820/
https://www.ncbi.nlm.nih.gov/pubmed/32647483
http://dx.doi.org/10.1016/j.jsps.2020.06.001

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