Contribution of Lysosome and Sigma Receptors to Neuroprotective Effects of Memantine Against Beta-Amyloid in the SH-SY5Y Cells

Purpose: Memantine is an approved drug for the treatment of Alzheimer’s disease (AD). Autophagy, lysosome dysfunction, and sigma receptors have possible roles in the pathophysiology of AD. Therefore, we aimed to investigate the contribution of sigma receptors and lysosome inhibition to the neuroprot...

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Detalles Bibliográficos
Autores principales: Keshavarz, Mojtaba, Farrokhi, Majid Reza, Amirinezhad Fard, Elahe, Mehdipour, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335986/
https://www.ncbi.nlm.nih.gov/pubmed/32665905
http://dx.doi.org/10.34172/apb.2020.055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335986/
https://www.ncbi.nlm.nih.gov/pubmed/32665905
http://dx.doi.org/10.34172/apb.2020.055

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